Prof. George A. Farber, Sr., MD
Col. U.S.A. (R), U.S.A.F, M.C. (Ret)
Founder, President American Academy of Medical Detectives (AAOMD)
3708 N Loyola Dr, Kenner. LA. Apt 115.
Kenner, LA 70065
504-583-4593
This article is prepared at a reader level between Certified MDs, Public Health personnel, and ordinary citizens and businesspersons.
Zika is systemic, from the first moment of contact, either infected mosquitoes bites or Human Mucous Membrane contact, such as saliva (or other body fluids such as sexual activity, or transfusion).
Zika virus (RNA) enters the new host, (Man or Monkey) and at 48 to 72 hours, there are 10,000,000 live viruses in your body system! The system includes the entire organ system (See diagram above).
The virus initially depresses WBCs (White blood cell count). Later, there will be an increased WBC (Leukocytosis). Illness begins about 48-96 hours, in the form of lethargy; due to decrease in blood oxygen levels via red blood cells (RBCs), .This is because of decrease in pulmonary oxygenation, in part due to accumulation of live viruses, and lymphocytes in the bronchi and alveolar tissue, resulting in less RBC oxygenation.
The other early signs and symptoms can be fever, dermatitis, pruritus, smell and taste changes, followed by generalized erythematous dermatitis, except for palms and soles, at 7 to 14 days after inoculation. This generalized dermatitis is often called Erythema Multiforme, which can be fatal!
Later signs/symptoms include jaundice, weakness, headaches, nausea, emesis, and shortness of breath. All of these later signs are ominous.
Individuals with chronic hepatitis, or who are pregnant are at high risk.
The vascular target pathology site is the dermo-epidermal junction, at the end of the arterial flow in the skin, and at the equivalent site of all the internal body organs. This specific site is at the junction of the terminal arteriole-venule vascular change. This microscopic anatomical site is where a micro-infarct occurs. This insult involves every organ in the body and is only visible (while alive) on the skin. See anatomical chart.
Zika is lifelong! The same is true for measles, chicken pox (varicella) and many other RNA viral diseases.
Further impact of Zika to follow this article.
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